KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTBK1
All Species:
10
Human Site:
S540
Identified Species:
36.67
UniProt:
Q5TCY1
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCY1
NP_115927.1
1321
142737
S540
A
E
E
E
D
F
D
S
K
E
W
V
I
I
D
Chimpanzee
Pan troglodytes
XP_001155217
1244
137355
G529
N
T
P
E
Q
A
D
G
G
G
S
N
G
F
I
Rhesus Macaque
Macaca mulatta
XP_001088342
1347
145334
S563
A
E
E
E
D
F
D
S
K
E
W
V
I
I
D
Dog
Lupus familis
XP_544644
1335
147975
G620
N
T
P
E
Q
A
D
G
G
A
S
N
G
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN3
1308
141595
S541
A
E
E
E
D
F
D
S
K
E
W
V
I
I
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514783
557
61177
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787864
2273
252079
T841
E
V
P
Q
E
R
S
T
S
P
K
P
F
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
95.8
35.9
N.A.
89.8
N.A.
N.A.
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.1
Protein Similarity:
100
48.1
96.1
48.6
N.A.
91.9
N.A.
N.A.
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.2
P-Site Identity:
100
13.3
100
13.3
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
0
0
0
29
0
0
0
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
43
0
72
0
0
0
0
0
0
0
43
% D
% Glu:
15
43
43
72
15
0
0
0
0
43
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
43
0
0
0
0
0
0
15
29
0
% F
% Gly:
0
0
0
0
0
0
0
29
29
15
0
0
29
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
43
43
29
% I
% Lys:
0
0
0
0
0
0
0
0
43
0
15
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
29
0
0
0
0
0
0
0
0
0
0
29
0
0
0
% N
% Pro:
0
0
43
0
0
0
0
0
0
15
0
15
0
0
0
% P
% Gln:
0
0
0
15
29
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
15
43
15
0
29
0
0
0
15
% S
% Thr:
0
29
0
0
0
0
0
15
0
0
0
0
0
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
0
43
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _